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This manuscript is supported by a grant from Pediatric Cancer Research Foundation (PCRF), Pediatric Cancer Foundation (PCF), and Leadiant Biosciences, Inc. (MC). The authors would like to thank the patients and their families who participated in the trial. We would also like to thank Virginia Davenport, RN, and Erin Morris, RN for their editorial assistance and the Data Safety Monitoring Committee: Oussama Abla, MD, Michelle Hermiston, MD, Sharon Bergeron, RN, and Joseph Laver, MD.
Conflict of interest
MC is on the advisory board for Jazz Pharmaceuticals and Nektar Therapeutics and the speaker bureau for Jazz Pharmaceuticals, Servier Pharmaceuticals, Sanofi Pharmaceuticals and Amgen, Inc. SG is on the speaker bureau for Jazz Pharmaceuticals. All other authors declare no conflict of interest.
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Presented in part at the Sixth International Symposium on Childhood, Adolescent and Young Adult non-Hodgkin lymphoma, 2018, Rotterdam, Netherlands.
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Goldman, S., Barth, M., Shiramizu, B. et al. A dose substitution of anthracycline intensity with dose-dense rituximab in children and adolescents with good-risk mature B-cell lymphoma. Leukemia (2021). https://doi.org/10.1038/s41375-021-01256-8