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HM is supported in part by the HHS Research Early Career Award from Hamilton Health Sciences Foundation. This investigation was supported by funding from Myeloma Canada. This study was supported by ICES, which is funded by an annual grant from the Ontario Ministry of Health and Long-Term Care (MOHLTC). The opinions, results and conclusions reported in this article are those of the authors and are independent from the funding sources. No endorsement by ICES or the Ontario MOHLTC is intended or should be inferred. Parts of this material are based on data and/or information compiled and provided by the Canadian Institute for Health Information (CIHI). However, the analyses, conclusions, opinions and statements expressed in the material are those of the authors, and not necessarily those of CIHI. We acknowledge Cancer Care Ontario for access to the Ontario Cancer Registry (OCR), Cancer Activity Level Reporting (ALR), Symptom Management Database (ESAS) and The New Drug Funding Program (NDFP). We thank IQVIA Solutions Canada Inc. for use of their Drug Information Database. SG is supported in part by the Walter B Frommeyer Fellowship in Investigative Medicine, Department of Medicine, University of Alabama at Birmingham
Conflict of interest
HS: Consultancy/Honoraria fees from Celgene, Takeda, Janssen, Amgen, Sanofi, SG: Reports research funding from CareVive, PackHealth, Sanofi and Oncopeptides. Honoraria from Carevive, Janssen, GP: Has a close family member who is employed by Roche Canada, and who owns Roche Canada stock. Consultancy fees from Astra-Zeneca. Honorarium from Takeda, TW: reports Research funding from Janssen and is a consultant for Carevive Systems and Seattle Genetics, AB, BS, AM, HS: None.
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Mian, H.S., Giri, S., Wildes, T.M. et al. External validation of the FIRST trial’s simplified frailty score in a population-based cohort. Leukemia (2021). https://doi.org/10.1038/s41375-021-01247-9