CHRONIC MYELOGENOUS LEUKEMIA

Conditional relative survival among adult patients with chronic myeloid leukemia in the tyrosine kinase inhibitor era: a population-based study in the Netherlands

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Fig. 1: Conditional 5-year relative survival up to 10 years post-diagnosis among adult patients with chronic myeloid leukemia in the Netherlands.

References

  1. 1.

    Hochhaus A, Larson RA, Guilhot F, Radich JP, Branford S, Hughes TP, et al. Long-term outcomes of Imatinib treatment for chronic myeloid leukemia. N Engl J Med. 2017;376:917–27.

    CAS  Article  Google Scholar 

  2. 2.

    Ector G, Visser O, Westerweel PE, Janssen J, Blijlevens NMA, Dinmohamed AG. Primary therapy and relative survival among elderly patients with chronic myeloid leukemia: a population-based study in the Netherlands, 1989–2017. Leukemia. 2020;34:3408–12.

    Article  Google Scholar 

  3. 3.

    Radivoyevitch T, Weaver D, Hobbs B, Maciejewski JP, Hehlmann R, Jiang Q, et al. Do persons with chronic myeloid leukaemia have normal or near normal survival? Leukemia. 2020;34:333–5.

    Article  Google Scholar 

  4. 4.

    Sant M, Minicozzi P, Mounier M, Anderson LA, Brenner H, Holleczek B, et al. Survival for haematological malignancies in Europe between 1997 and 2008 by region and age: results of EUROCARE-5, a population-based study. Lancet Oncol. 2014;15:931–42.

    Article  Google Scholar 

  5. 5.

    Huang X, Cortes J, Kantarjian H. Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Cancer. 2012;118:3123–7.

    Article  Google Scholar 

  6. 6.

    Janssen-Heijnen ML, Gondos A, Bray F, Hakulinen T, Brewster DH, Brenner H, et al. Clinical relevance of conditional survival of cancer patients in europe: age-specific analyses of 13 cancers. J Clin Oncol. 2010;28:2520–8.

    Article  Google Scholar 

  7. 7.

    Hieke S, Kleber M, Konig C, Engelhardt M, Schumacher M. Conditional survival: a useful concept to provide information on how prognosis evolves over time. Clin Cancer Res. 2015;21:1530–6.

    Article  Google Scholar 

  8. 8.

    Schouten LJ, Hoppener P, van den Brandt PA, Knottnerus JA, Jager JJ. Completeness of cancer registration in Limburg, The Netherlands. Int J Epidemiol. 1993;22:369–76.

    CAS  Article  Google Scholar 

  9. 9.

    Dickman PW, Adami HO. Interpreting trends in cancer patient survival. J Intern Med. 2006;260:103–17.

    CAS  Article  Google Scholar 

  10. 10.

    Henson DE, Ries LA. The relative survival rate. Cancer. 1995;76:1687–8.

    CAS  Article  Google Scholar 

  11. 11.

    Ederer F, Heise H. Instructions to IBM 650 programmers in processing survival computations. Methodological note No. 10. End results evaluation section. Bethesda MD: National Cancer Institute; 1959.

  12. 12.

    Brenner H, Rachet B. Hybrid analysis for up-to-date long-term survival rates in cancer registries with delayed recording of incident cases. Eur J Cancer. 2004;40:2494–501.

    Article  Google Scholar 

  13. 13.

    Dickman PW, Coviello E. Estimating and modeling relative survival. Stata J. 2015;15:186–215.

    Article  Google Scholar 

  14. 14.

    Brenner H, Gondos A, Pulte D. Recent trends in long-term survival of patients with chronic myelocytic leukemia: disclosing the impact of advances in therapy on the population level. Haematologica. 2008;93:1544–9.

    Article  Google Scholar 

  15. 15.

    Sasaki K, Kantarjian HM, Jain P, Jabbour EJ, Ravandi F, Konopleva M, et al. Conditional survival in patients with chronic myeloid leukemia in chronic phase in the era of tyrosine kinase inhibitors. Cancer. 2016;122:238–48.

    CAS  Article  Google Scholar 

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Acknowledgements

The authors would like to thank the registration clerks of the Netherlands Cancer Registry (NCR) for their dedicated data collection. The nationwide population-based NCR is maintained and hosted by the Netherlands Comprehensive Cancer Organisation (IKNL).

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AGD designed the study; GICGE analyzed the data; AGD supervised the data analyses; OV was responsible for the data collection; GICGE wrote the manuscript with contributions from all authors, who also interpreted the data, and read, commented on, and approved the final version of the manuscript.

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Correspondence to Geneviève I. C. G. Ector.

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Ector, G.I.C.G., Visser, O., Posthuma, E.F.M. et al. Conditional relative survival among adult patients with chronic myeloid leukemia in the tyrosine kinase inhibitor era: a population-based study in the Netherlands. Leukemia (2021). https://doi.org/10.1038/s41375-021-01174-9

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