Stem cell transplantation

Impact of Nrf2 expression in reconstituting T-cells of allogeneic hematopoietic stem cell transplanted patients

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Fig. 1: Nrf2 levels in reconstituting T-cells after allo-HSCT.
Fig. 2: Impact of Nrf2 levels on T-cell exhaustion phenotype and clinical outcome.


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We are grateful to the patients, their families, and referring physicians who made this study possible. We thank Alina Kämpf (Core Unit Cell Sorting and Immunomonitoring, Erlangen) for excellent support. FK, RB, RJ, AM, and DM were funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - Project-ID 324392634 - TRR 221.

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FK performed research, analyzed data, and helped writing the manuscript. AS, RL, MB, BJ, and RB performed research and analyzed data. SV and WR provided patient material and clinical data. AM helped designing the study. DM designed the study, analyzed data, and wrote the manuscript.

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Correspondence to Dimitrios Mougiakakos.

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Karl, F., Stoll, A., Böttcher-Loschinski, R. et al. Impact of Nrf2 expression in reconstituting T-cells of allogeneic hematopoietic stem cell transplanted patients. Leukemia (2020).

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