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Chronic myelogenous leukemia

BCR-ABL1 compound mutants: prevalence, spectrum and correlation with tyrosine kinase inhibitor resistance in a consecutive series of Philadelphia chromosome-positive leukemia patients analyzed by NGS

Leukemia volume 35, pages 2102–2107 (2021)Cite this article

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Fig. 1: Frequency and type of CMs in Ph+ leukemia patients.

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Author notes

  1. Giovanni Martinelli

    Present address: Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy

Authors and Affiliations

  1. Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “L. e A. Seràgnoli”, University of Bologna, Bologna, Italy

    Simona Soverini, Margherita Martelli, Luana Bavaro, Caterina De Benedittis, Michele Baccarani & Giovanni Martinelli

  2. Fondazione Policlinico Universitario A Gemelli-IRCCS, Istituto di Ematologia e Università Cattolica del Sacro Cuore, Rome, Italy

    Simona Sica & Federica Sorà

  3. Hematology Division, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

    Alessandra Iurlo

  4. Department of Medicine, Section of Hematology, University of Verona, Verona, Italy

    Massimiliano Bonifacio

  5. Hematology Unit, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, Turin, Italy

    Patrizia Pregno

  6. Department of Clinical and Experimental Medicine, Section of Hematology, University of Pisa, Pisa, Italy

    Sara Galimberti

  7. Hematology and BMT Unit, San Raffaele Scientific Institute IRCCS, Milan, Italy

    Francesca Lunghi

  8. Department of Emergency and Organ Transplantation (D.E.T.O.), Hematology Section, University of Bari, Bari, Italy

    Francesco Albano

  9. Hematology Unit, Spedali Civili Azienda Ospedaliera, Brescia, Italy

    Mariella D’Adda

  10. Division of Hematology, Azienda Ospedialiero-Universitaria, Parma, Italy

    Monica Crugnola

  11. Hematology Unit, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy

    Isabella Capodanno

  12. Azienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia

    Fausto Castagnetti, Gabriele Gugliotta, Cristina Papayannidis, Gianantonio Rosti & Michele Cavo

  13. Istituto di Ematologia “Seràgnoli”, Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italia

    Fausto Castagnetti, Gabriele Gugliotta, Cristina Papayannidis, Gianantonio Rosti & Michele Cavo

  14. Unit of Medical Genetics, University of Parma, Parma, Italy

    Antonio Percesepe

  15. Department of Science and Innovation Technology (DISIT), University of Piemonte Orientale, Alessandria, Italy

    Flavio Mignone

Authors
  1. Simona Soverini
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Corresponding author

Correspondence to Simona Soverini.

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Conflict of interest

SS has received speaker fees from Incyte Biosciences. SSi has received honoraria for advisory boards from Incyte Biosciences. AI has received honoraria from Novartis, Pfizer and Incyte Biosciences. MB has received honoraria from Novartis, Incyte Biosciences, Pfizer. PP has received honoraria from Novartis, Incyte Biosciences, Bristol-Myers Squibb, Pfizer. SG has received speaker fees from Pfizer, Novartis, Incyte Biosciences. FA has received honoraria for advisory boards from Incyte Biosciences. FC has received honoraria from Novartis, Bristol‐Myers Squibb, Pfizer, Incyte Biosciences. GG has received honoraria from Novartis and Bristol‐Myers Squibb. GR has received honoraria from Novartis, Bristol-Myers Squibb, Pfizer, Incyte Biosciences. GM has been a consultant and has received speaker fees from Incyte Biosciences, Pfizer. The remaining authors declare that they have no competing interests.

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Soverini, S., Martelli, M., Bavaro, L. et al. BCR-ABL1 compound mutants: prevalence, spectrum and correlation with tyrosine kinase inhibitor resistance in a consecutive series of Philadelphia chromosome-positive leukemia patients analyzed by NGS. Leukemia 35, 2102–2107 (2021). https://doi.org/10.1038/s41375-020-01098-w

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