Lymphoma

Interferon-free compared to interferon-based antiviral regimens as first-line therapy for B-cell lymphoproliferative disorders associated with hepatitis C virus infection

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Funding

The research leading to these results has received funding from AIRC under IG 2017—ID. 20767 project—P.I. Luca Arcaini and from “Ricerca Corrente Fondazione IRCCS Policlinico San Matteo”—P.I. Luca Arcaini. The ANRS-CO22 HEPATHER cohort was sponsored and funded by ANRS (France REcherche Nord & Sud Sida-HIV Hépatites). The sponsor has not participated in the statistical analysis and interpretation of data, in the writing the manuscript, and in the decision to submit the work for publication.

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Contributions

MF, LA, OH, and CB designed and supervised the overall conduction of the study; VVF, LA, and MF analyzed the data; MF and LA wrote the paper; M.F. and LA collected the data; MF, CB, CV, HF, MGo, MV, AP, HAT, JPO, RR, FZ, LR, MMe, CD, CA, FP, MGe, AF, MP, LN, SR, AF, MMi, EC, ID, RB, OH, and LA enrolled and cared for the patients; MF, CB, OH, and LA. reviewed the paper and all authors approved the final paper.

Corresponding author

Correspondence to Luca Arcaini.

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Conflict of interest

LA received advisory honoraria from Bayer, Celgene, Gilead, Roche, Sandoz, Verastem and research support from Gilead. HAT is or has been the principal investigator for research grants from Gilead Sciences, Merck & Co., Inc., and Vertex Pharmaceuticals, with all funds paid to MD Anderson. HAT also is or has been a paid scientific advisor for Gilead Sciences, Janssen Pharmaceuticals, Inc., Merck & Co., Inc., Vertex Pharmaceuticals, Genentech, Novartis, Astellas Pharma, Pfizer Inc., and Theravance Biopharma, Inc.; the terms of these arrangements are being managed by MD Anderson in accordance with its conflict of interest policies. AP received advisory honoraria from Roche, Merck, Pfyzer, Sandoz, Takeda.

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Frigeni, M., Besson, C., Visco, C. et al. Interferon-free compared to interferon-based antiviral regimens as first-line therapy for B-cell lymphoproliferative disorders associated with hepatitis C virus infection. Leukemia 34, 1462–1466 (2020). https://doi.org/10.1038/s41375-019-0687-2

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