Table 2 Baseline characteristics by frailty group

From: A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial

CharacteristicNonfrail (n = 828)Frail (n = 790)
Age, n (%)
  Median (range), years70 (40–80)77 (44–92)
  <65 years66 (8)26 (3)
  65–75 years754 (91)299 (38)
  76–80 years74 (9)290 (37)
  >80 years0201 (25)
Sex, n (%)
  Male436 (53)415 (53)
  Female392 (47)375 (47)
ECOG performance status, n (%)a
  0401 (48)73 (9)
  1427 (52)368 (47)
  20343 (43)
  306 (<1)
  Data not available00
International Staging System stage, n (%)b
  I or II575 (69)419 (53)
  III253 (31)371 (47)
Lactate dehydrogenase, n (%)
  <200 U/L707 (85)612 (78)
  ≥200 U/L120 (15)177 (22)
 Missing data11
Creatinine clearance, n (%)
  <60 mL/min299 (36)478 (61)
  <30 mL/min38 (5)108 (14)
  ≥60 mL/min529 (64)312 (39)
  1. ECOG Eastern Cooperative Oncology Group
  2. aECOG scores range from 0 to 5, with higher numbers indicating greater disability
  3. bHigher stages indicate more severe disease