Fig. 2 | Leukemia

Fig. 2

From: Clinical, histopathological and molecular characterization of hypoplastic myelodysplastic syndrome

Fig. 2

Patterns of the genetic lesions identified in the study cohort. a Distribution of somatic genetic lesions in AA, h-MDS, and n-MDS according to the final diagnosis, resulting from standard work-up. Blue bar indicates absence of genetic lesions, maroon bar denotes cytogenetic abnormalities, green bar somatic mutations, orange bar cytogenetic abnormality and somatic mutation. b Distribution of somatic genetic lesions proven specific for MDS in AA, h-MDS, and n-MDS according to the final diagnosis, resulting from standard work-up. Blue bar indicates absence of specific genetic lesions, maroon bar represents cytogenetic abnormalities providing presumptive evidence of MDS according to WHO criteria, green bar denotes somatic mutation patterns proven highly specific for MDS according to Malcovati et al. [36] c Distribution of somatic mutations in the analyzed genes according to the final diagnosis, resulting from standard work-up. Red color indicates a diagnosis of n-MDS, green of h-MDS, blue of AA. Each column represents an individual patient sample

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