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We thank Dr. Madeleine Carreau (Laval University) for the Fanca+/− mice, the Vector Core of the Cincinnati Children’s Research Foundation (Cincinnati Children’s Hospital Medical Center) for the preparation of retroviruses, and the Comprehensive Mouse and Cancer Core of the Cincinnati Children’s Research Foundation (Cincinnati Children’s Hospital Medical Center) for bone marrow transplantation service. This work was supported by NIH grants R01 CA193350, R01 DK104814, R01 CA150547, R01 HL076712, and R01 HD089932. Q.P. and J.M. were Leukemia and Lymphoma Scholar. W.D. was supported by the NIH T32 HL091805 training grant. The studies were further supported by a NIH center grant P30 DK090971.