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Co-first authors: Jonathan Bond and Elise Labis.

Co-directing authors: Jonathan Bond and Hélène Lapillonne.


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The current study was supported by the Institut National du Cancer Projet Caramel (INCA-DGOS_5797). The ELAM02 trial was supported by a grant from the French Ministry of Health (PHRC-K 2003 no 03142) and was sponsored by the Assistance Publique-Hôpitaux de Paris (Département de la Recherche Clinique et du Développement). We would like to thank all patients, families, and staff at participating centers in the trial. JB was supported by a Kay Kendall Leukemia Fund Intermediate Research Fellowship. The Necker laboratory also received funding from the Association Laurette Fugain and La ligue contre le Cancer. The Trousseau laboratory was also supported by the Association Laurette Fugain and La Fondation de France.

Author information

Author notes

    • Jonathan Bond

    Present address: School of Medicine and Systems Biology Ireland, University College Dublin, Dublin 4, Ireland


  1. Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut national de recherche médicale (INSERM) U1151, Paris, France

    • Jonathan Bond
    • , Guillaume Hypolite
    • , Vahid Asnafi
    •  & Elizabeth Macintyre
  2. Laboratory of Onco-Haematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France

    • Jonathan Bond
    • , Guillaume Hypolite
    • , Vahid Asnafi
    •  & Elizabeth Macintyre
  3. Medical Genetics Institute, Jeanne de Flandre Hospital, Centre Hospitalier Universitaire (CHU), Lille, France

    • Elise Labis
  4. Cancer Research Institute, INSERM Unité Mixte de Recherche (UMR)-S 1172, F-59000, Lille, France

    • Elise Labis
    • , Alice Marceau-Renaut
    • , Nicolas Duployez
    •  & Claude Preudhomme
  5. CHU Lille, Laboratory of Hematology, F-59000, Lille, France

    • Alice Marceau-Renaut
    • , Nicolas Duployez
    •  & Claude Preudhomme
  6. Clinical Haematology and Cellular Therapy Department, Hospital Saint-Antoine, APHP, Paris, France

    • Myriam Labopin
  7. EBMT ALWP Office, Hôpital Saint-Antoine, APHP, Paris, France

    • Myriam Labopin
  8. Universite Pierre et Marie Curie Univ Paris 06, Paris, France

    • Myriam Labopin
    •  & Hélène Lapillonne
  9. INSERM UMRs 938, CDR Saint-Antoine, F-75012, Paris, France

    • Myriam Labopin
    •  & Hélène Lapillonne
  10. Department of Pediatric Haematology, University Hospital of La Timone, Marseille, France

    • Gérard Michel
  11. Department of Pediatric Hematology and Oncology, Children’s Hospital, Bordeaux, France

    • Stéphane Ducassou
  12. Department of Pediatric Haematology and Oncology, Hôpital Armand Trousseau, AP-HP, Paris, France

    • Hélène Boutroux
    • , Arnaud Petit
    •  & Guy Leverger
  13. Department of Pediatric Hematology-Oncology, Jeanne de Flandre Hospital, CHRU, Lille, France

    • Brigitte Nelken
  14. Institute of Pediatric Haematology and Oncology, Hospices Civils de Lyon, Lyon, France

    • Yves Bertrand
  15. Department of Pediatric Hematology and Immunology, AP-HP, Robert Debré Hospital, Paris, France

    • André Baruchel
  16. Haematology Laboratory, Hôpital Armand Trousseau, AP-HP, Paris, France

    • Hélène Lapillonne


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Conflict of interest

The authors declare that they have no conflict of interest.

Corresponding authors

Correspondence to Jonathan Bond or Hélène Lapillonne.

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