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Method of home tube feeding and 2–3-year neurodevelopmental outcome

Abstract

Objective

To describe the Bayley Scales of Infant Development 3rd Edition (Bayley-III) of infants discharged home receiving tube feeds.

Study design

Retrospective review of infants discharged with nasogastric or gastrostomy tube feeds and completed a Bayley-III assessment at 2–3-years of age through a neonatal follow-up program. Results were reported using descriptive statistics.

Results

Of infants discharged with nasogastric feeds, median Bayley-III scores were in the low-average to average range, and full oral feeds were achieved in 75%. Of infants discharged with gastrostomy tube feeds, median Bayley-III scores were in the extremely low range, and full oral feeds were achieved in 36%. Our data set did not demonstrate a distinct patient demographic that correlated to the type of feeding tube at discharge.

Conclusion

Neurodevelopmental outcome at 2–3 years does not appear to be negatively impacted by the decision to discharge an infant from the NICU with home NG feedings.

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Fig. 1: Home feeding algorithm.
Fig. 2: Bayley-III scores at 2–3 years of age based on feeding methods.

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Data availability

The data used to support the findings of this study is available from the corresponding authors upon reasonable request.

References

  1. Jefferies AL. Going home: facilitating discharge of the preterm infant. Paediatr Child Health. 2014;19:31–6.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Smith VC, Love K, Goyer E. NICU discharge preparation and transition planning: guidelines and recommendations. J Perinatol. 2022;42:7–21.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Amaizu N, Shulman R, Schanler R, Lau C. Maturation of oral feeding skills in preterm infants. Acta Paediatr. 2008;97:61.

    Article  CAS  PubMed  Google Scholar 

  4. Shaker CS. Infant-guided, co-regulated feeding in the neonatal intensive care unit. Part II: interventions to promote neuroprotection and safety. Semin Speech Lang. 2017;38:106–15.

    Article  PubMed  Google Scholar 

  5. Ermarth A, Ling CY. Partial enteral discharge programs for high-risk infants. NeoReviews. 2022;23:e13–22.

    Article  PubMed  Google Scholar 

  6. Jadcherla S, Khot T, Moore R, Malkar M, Gulati I, Slaughter J. Feeding methods at discharge predict long-term feeding and neurodevelopmental outcomes in preterm infants referred for gastrostomy evaluation. J Pediatr. 2017;181:125.

    Article  PubMed  Google Scholar 

  7. Warren M, Do B, Das A, Smith PB, Adams-Chapman I, Jadcherla S, et al. Gastrostomy tube feeding in extremely low birthweight infants: frequency, associated comorbidities, and long-term outcomes. J Pediatr. 2019;214:41.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Vermilyea S, Goh VL. Enteral feedings in children. Nutr Clin Pract. 2016;31:59–67.

    Article  CAS  PubMed  Google Scholar 

  9. White BR, Ermarth A, Thomas D, Arguinchona O, Presson AP, Ling CY. Creation of a standard model for tube-feeding at NICU discharge. J Parenter Enter Nutr. 2020;44:491.

    Article  Google Scholar 

  10. Fisher C, Haag M, Douglas A, Kayhani A, Warren JB. Remote monitoring for neonates requiring continued nasogastric tube feeding: implementation, patient characteristics, and early outcomes. J Perinatol. 2023;43:1125–30.

    Article  PubMed  Google Scholar 

  11. Vergales BD, Murray PD, Miller SE, Vergales JE. Safety and efficacy of a home nasogastric monitoring program for premature infants. J Neonatal Perinat Med. 2022;15:165–70.

    Article  Google Scholar 

  12. Williams SL, Popowics NM, Tadesse DG, Poindexter BB, Merhar SL. Tube feeding outcomes of infants in a Level IV NICU. J Perinatol. 2019;39:1406–10.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Khalil ST, Uhing MR, Duesing L, Visotcky A, Tarima S, Nghiem-Rao TH. Outcomes of infants with home tube feeding: comparing nasogastric versus gastrostomy tubes. J Parenter Enter Nutr. 2017;41:1380.

    Article  Google Scholar 

  14. Duncan TL, Ulugia J, Bucher BT. Association of gastrostomy placement on hospital readmission in premature infants. J Perinatol. 2019;39:1485.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Ermarth A, Thomas D, Ling CY, Cardullo A, White BR. Effective tube weaning and predictive clinical characteristics of NICU patients with feeding dysfunction. J Parenter Enter Nutr. 2020;44:920–7.

    Article  Google Scholar 

  16. Mago-Shah DD, Malcolm WF, Greenberg RG, Goldstein RF. Discharging medically complex infants with supplemental nasogastric tube feeds: impact on neonatal intensive care unit length of stay and prevention of gastrostomy tubes. Am J Perinatol. 2021;38:E207–14.

    Article  PubMed  Google Scholar 

  17. Collins CT, Makrides M, McPhee AJ. Early discharge with home support of gavage feeding for stable preterm infants who have not established full oral feeds. Cochrane Database Syst Rev. 2015;2015:CD003743.

    PubMed  PubMed Central  Google Scholar 

  18. Meerlo-Habing AE, Kosters-Boes EA, Klip H, Brand PLP. Early discharge with tube feeding at home for preterm infants is associated with longer duration of breast feeding. Arch Dis Child Fetal Neonatal Ed. 2009;94:294–7.

    Article  Google Scholar 

  19. Charpak N, Ruiz-Peláez JG, Charpak Y. Rey-Martinez Kangaroo Mother Program: an alternative way of caring for low birth weight infants? One year mortality in a two cohort study. Pediatrics. 1994;94:804–10.

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

Authors

Contributions

AF, AE, CYL, KB, and TLD designed the study. AF and TLD acquired the data and performed analysis and interpretation. AF, AE, CYL, KB, and TLD wrote the manuscript. All authors approved the final version of the manuscript.

Corresponding author

Correspondence to Tara L. DuPont.

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The authors declare no competing interests.

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Ethical approval with a waiver of consent was obtained from the University of Utah Institutional Review Board.

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Fisher, A., Ermarth, A., Ling, C.Y. et al. Method of home tube feeding and 2–3-year neurodevelopmental outcome. J Perinatol (2024). https://doi.org/10.1038/s41372-024-02013-2

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