Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Journal Club
  • Published:

Does umbilical cord milking reduce neonatal intensive care unit admission in non-vigorous infants born at 35–42 weeks’ gestation?

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Katheria AC, Clark E, Yoder B, Schmölzer GM, Law BHY, El-Naggar W, et al. Umbilical cord milking in nonvigorous infants: a cluster-randomized crossover trial. Am J Obstet Gynecol. 2023;228:217.e1–217.e14.

    Article  PubMed  Google Scholar 

  2. Oh W, Wallgren G, Hanson JS, Lind J. The effects of placental transfusion on respiratory mechanics of normal term newborn infants. Pediatrics. 1967;40:6–12.

    Article  CAS  PubMed  Google Scholar 

  3. Erickson-Owens DA, Mercer JS, Oh W. Umbilical cord milking in term infants delivered by cesarean section: a randomized controlled trial. J Perinatol. 2012;32:580–4.

    Article  CAS  PubMed  Google Scholar 

  4. Upadhyay A, Gothwal S, Parihar R, Garg A, Gupta A, Chawla D, et al. Effect of Umbilical Cord Milking in Term and Near Term Infants: Randomized Control Trial. Obstetrical Gynecol Surv. 2013;68:333–4.

    Article  Google Scholar 

  5. Consonni S, Tessitore IV, Conti C, Plevani C, Condo’ M, Torcasio F, et al. Umbilical cord management strategies at cesarean section. J Obstet Gynaecol Res. 2020;46:2590–7.

    Article  Google Scholar 

  6. Chiruvolu A, George R, Stanzo KC, Kindla CM, Desai S. Effects of Placental Transfusion on Late Preterm Infants Admitted to a Mother–Baby Unit. Am J Perinatol. 2022;39:1812–9.

    Article  PubMed  Google Scholar 

  7. Yasa B, Gonen I, Dincer E, Babayigit A, Saglam O, Cetinkaya M. Different Placental Transfusion Strategies and Their Effects on Short - Term Hematological Parameters in Term Infants. Iran J Pediatrics. 2023;33:e133597.

  8. Seliga-Siwecka JP, Puskarz-Gasowska J, Tolloczko J. The risk of hyperbilirubinemia in term neonates after placental transfusion - a randomized-blinded controlled trial. Ginekologia Pol. 2020;91:613–9.

    Article  Google Scholar 

  9. Ortiz-Esquinas I, Gomez-Salgado J, Rodriguez-Almagro J, Arias-Arias A, Ballesta-Castillejos A, Hernandez-Martinez A. Umbilical Cord Milking in Infants Born at < 37 Weeks of Gestation: A Systematic Review and Meta-Analysis. J Clin Med. 2020;9:1071.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Katheria AC, Law BHY, Poeltler D, Rich W, Ines F, Schmölzer GM, et al. Cardiac and cerebral hemodynamics with umbilical cord milking compared with early cord clamping: A randomized cluster crossover trial. Early Hum Dev. 2023;177–178:105728.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Higgins JP, Eldridge S, Li T. Chapter 23: Including variants on randomized trials. In: Higgins JP, Eldridge S, Li T, editors. Cochrane Handbook for Systematic Reviews of Interventions. Version 6.4. 2023. Available from: https://training.cochrane.org/handbook/current.

  12. Katheria A, Reister F, Essers J, Mendler M, Hummler H, Subramaniam A, et al. Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping With Death or Severe Intraventricular Hemorrhage Among Preterm Infants. JAMA. 2019;322:1877–86.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Kumbhat N, Eggleston B, DeMauro SB, Meurs KPV, Foglia EE, Lakshminrusimha S, et al. Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants. J Pediatr. 2021;232:87–94.e4.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Hemming K, Taljaard M, Weijer C, Forbes AB. Use of multiple period, cluster randomised, crossover trial designs for comparative effectiveness research. BMJ. 2020;371:m3800.

    Article  PubMed  Google Scholar 

  15. Grantham KL, Kasza J, Heritier S, Hemming K, Litton E, Forbes AB. How many times should a cluster randomized crossover trial cross over? Stat Med. 2019;38:5021–33.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The Journal Club is a collaboration between the American Academy of Pediatrics- Section of Neonatal-Perinatal Medicine and the International Society for Evidence-based Neonatology (EBNEO.org).

Author information

Authors and Affiliations

Authors

Contributions

AW conceptualized and drafted the initial manuscript. AW and SR reviewed and approved the final draft of the manuscript and are accountable for its accuracy.

Corresponding author

Correspondence to Amanda E. Winkler.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Winkler, A.E., Roumiantsev, S. Does umbilical cord milking reduce neonatal intensive care unit admission in non-vigorous infants born at 35–42 weeks’ gestation?. J Perinatol 44, 924–927 (2024). https://doi.org/10.1038/s41372-024-01960-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41372-024-01960-0

Search

Quick links