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Is erythropoietin beneficial and safe as an adjunctive therapy to therapeutic hypothermia in newborns with hypoxic ischemic injury?

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The Journal Club is a collaboration between the American Academy of Pediatrics – Section of Neonatal Perinatal Medicine and the International Society of Evidence-Based Neonatology (

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Authors and Affiliations



ALM conducted literature review and primarily drafted the manuscript. JLS and KLB assisted by providing supplementary resources for review, offering edits and design modifications, and revising additional drafts. SC offered edits and oversight to sections discussing statistical analysis. All authors reviewed and agreed upon the final submission.

Corresponding author

Correspondence to Abigail L. Melemed.

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Competing interests

All authors have denied any direct conflicts of interest in regard to funding or financial gain relevant to this manuscript. Of note, Dr. Benninger was involved in the HEAL consortium and is included among the original authors of the 2022 article that is cited. Additionally, Dr. Slaughter is a principal investigator of the PIVOTAL trial which receives supplementary grant funding from Abbott in addition to grant funding from the National Heart, Lung, and Blood Institute (NHLBI) (UH3 HL161338).

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Melemed, A.L., Slaughter, J.L., Benninger, K.L. et al. Is erythropoietin beneficial and safe as an adjunctive therapy to therapeutic hypothermia in newborns with hypoxic ischemic injury?. J Perinatol (2023).

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