Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Postnatal fluid balance – it’s time to pay attention

Your institute does not have access to this article

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Valentine GC, Perez KM, Wood TR, Mayock DE, Comstock BA, Puia-Dumitrescu M, et al. Postnatal maximal weight loss, fluid administration, and outcomes in extremely preterm newborns. J Perinatol. 2022. https://doi.org/10.1038/s41372-022-01369-7

  2. Juul SE, Comstock BA, Wadhawan R, Mayock DE, Courtney SE, Robinson T, et al. A randomized trial of erythropoietin for neuroprotection in preterm infants. N. Engl J Med. 2020;382:233–43. https://doi.org/10.1056/NEJMoa1907423.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  3. Segar JL. A physiological approach to fluid and electrolyte management of the preterm infant: Review. J Neonatal Perinat Med. 2020;13:11–19. https://doi.org/10.3233/NPM-190309

    CAS  Article  Google Scholar 

  4. Lorenz JM, Kleinman LI, Kotagal UR, Reller MD. Water balance in very low-birth-weight infants: relationship to water and sodium intake and effect on outcome. J Pediatr. 1982;101:423–32. https://doi.org/10.1016/s0022-3476(82)80078-4.

    CAS  Article  PubMed  Google Scholar 

  5. Kavvadia V, Greenough A, Dimitriou G, Hooper R. Randomised trial of fluid restriction in ventilated very low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 2000;83:F91–6. https://doi.org/10.1136/fn.83.2.f91.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  6. Diderholm B, Normann E, Ahlsson F, Sindelar R, Ågren J. The impact of restricted versus liberal early fluid volumes on plasma sodium, weight change, and short-term outcomes in extremely preterm infants. Nutrients. 2022;14:795. https://doi.org/10.3390/nu14040795.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  7. Oh W, Poindexter BB, Perritt R, Lemons JA, Bauer CR, Ehrenkranz RA, et al. Association between fluid intake and weight loss during the first ten days of life and risk of bronchopulmonary dysplasia in extremely low birth weight infants. J Pediatr. 2005;147:786–90. https://doi.org/10.1016/j.jpeds.2005.06.039.

    Article  PubMed  Google Scholar 

  8. Wadhawan R, Oh W, Perritt R, Laptook AR, Poole K, Wright LL, et al. Association between early postnatal weight loss and death or BPD in small and appropriate for gestational age extremely low-birth-weight infants. J Perinatol. 2007;27:359–64. https://doi.org/10.1038/sj.jp.7211751.

    CAS  Article  PubMed  Google Scholar 

  9. Selewski DT, Gist KM, Nathan AT, Goldstein SL, Boohaker LJ, Akcan-Arikan A, et al. The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group. Pediatr Res. 2020;87:550–7. https://doi.org/10.1038/s41390-019-0579-1.

    CAS  Article  PubMed  Google Scholar 

  10. Soullane S, Patel S, Claveau M, Wazneh L, Sant’Anna G, Beltempo M. Fluid status in the first 10 days of life and death/bronchopulmonary dysplasia among preterm infants. Pediatr Res. 2021;90:353–8. https://doi.org/10.1038/s41390-021-01485-8.

    CAS  Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

HJS and JLS together contributed to the concept and outline for this project, the collection of appropriate references, the interpretation of studies, and draft and revision of the manuscript. Both HJS and JLS approved the final submitted version and agree to be accountable for all aspects of the work.

Corresponding author

Correspondence to Heidi J. Steflik.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Steflik, H.J., Segar, J.L. Postnatal fluid balance – it’s time to pay attention. J Perinatol 42, 985–986 (2022). https://doi.org/10.1038/s41372-022-01442-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41372-022-01442-1

Search

Quick links