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Resuscitation outcomes of infants that do not achieve a 5 min target SpO2 saturation

Journal of Perinatology volume 39, pages 1635–1639 (2019)Cite this article

Subjects

Abstract

Objective

To determine differences in the duration and level of resuscitation between infants that achieve a peripheral oxygen saturation (SpO2) of 80% by 5 min compared with those who remain below 80% saturation.

Study design

Infants < 32 weeks GA were analyzed. Pulse rate, SpO2, airway pressure, and fraction of inspired oxygen were collected during the first 10 min of life.

Results

Two hundred and eighty-four infants were analyzed of which 100 had SpO2 < 80% at 5 min of life. Composite outcome of death and any IVH was greater in the <80% at 5 min group. These infants had lower heart rates and lower SpO2 despite increased mean airway pressure and higher FiO2 (p < 0.001).

Conclusion

Infants <32 weeks GA that do not achieve a peripheral arterial saturation of 80% by 5 min of life experience more death or severe IVH. This association is amongst the strongest seen of any predictor of morbidity in the delivery room.

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Authors and Affiliations

  1. Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA

    Anup C. Katheria, Kasim Hassen, Wade Rich, Debra Poeltler & Neil Finer

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  1. Anup C. Katheria
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  2. Kasim Hassen
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  3. Wade Rich
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  4. Debra Poeltler
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Correspondence to Anup C. Katheria.

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Katheria, A.C., Hassen, K., Rich, W. et al. Resuscitation outcomes of infants that do not achieve a 5 min target SpO2 saturation. J Perinatol 39, 1635–1639 (2019). https://doi.org/10.1038/s41372-019-0491-x

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