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Maternal anemia and pregnancy outcomes: a population-based study

Journal of Perinatology volume 39, pages 911–919 (2019)Cite this article

Subjects

Abstract

Objective

This study aims to describe adverse maternal and neonatal outcomes in women diagnosed with anemia in pregnancy.

Study design

This was a retrospective cohort study of California live births from 2007–2012, linked to maternal and infant hospital discharge records. Relative risks of adverse maternal and neonatal outcomes were calculated for women with and without anemia.

Results

Anemic mothers were more likely to be diagnosed with hypertension, diabetes, placental abruption, or chorioamnionitis, or require a blood transfusion or admission to the intensive care unit (aRRs 1.2–6.8). Infants born to anemic mothers were more likely to be born preterm (8.9% versus 6.5%), but not more likely to suffer morbidities associated with prematurity.

Conclusion

In a population-based study, the diagnosis of anemia in pregnancy carries a higher risk of peri-partum, intra-partum, and post-partum complications for the mother, and a higher risk of preterm birth for the infant.

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Funding

The work was funded in part by the UCSF California Preterm Birth Initiative.

Author information

Authors and Affiliations

  1. Department of Pediatrics, University of California San Francisco, San Francisco, California, USA

    Rachael H. Beckert, James G. Anderson & Elizabeth E. Rogers

  2. Department of Pediatrics, University of California San Diego, La Jolla, California, USA

    Rebecca J. Baer

  3. California Preterm Birth Initiative, University of California San Francisco, San Francisco, California, USA

    Rebecca J. Baer

  4. Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA

    Laura L. Jelliffe-Pawlowski

Authors
  1. Rachael H. Beckert
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  2. Rebecca J. Baer
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Correspondence to Rachael H. Beckert.

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Beckert, R.H., Baer, R.J., Anderson, J.G. et al. Maternal anemia and pregnancy outcomes: a population-based study. J Perinatol 39, 911–919 (2019). https://doi.org/10.1038/s41372-019-0375-0

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