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Ambient temperature variability and blood pressure in a prospective cohort of 50,000 Chinese adults

Abstract

Blood pressure has been shown to change by outdoor temperature, but whether intra- and inter-day temperature variability (TV) will bring higher effect on BP is not clear. Based on a prospective cohort study, the mixed effect model was selected to estimate the relationship between TV (daily temperature variability (DTV) and hourly temperature variability (HTV)) and BP (systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and mean arterial pressure (MAP)) after adjusting for confounding variables. We found that there was a positive linear correlation between TV and BP. The results of DTV and HTV were basically consistent, but the effect estimates of HTV seemed to be larger. Gender, age, BMI, education level and BP status may modify the relationship between TV and BP. The effect of TV on BP was greater in non-heating season than in heating season. Our work contributes to a further macro mechanism evidence for the TV-CVDs association.

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Fig. 1: Exposure-relationship between TV and BP.
Fig. 2: BP changes associated with per 1 °C increase in DTV and HTV in different lag days.
Fig. 3: Estimated effects in BP per 1 °C increase in TV among people with different blood pressure.

Data availability

The data that support the findings in this research are available from the corresponding author ShanZheng upon reasonable request.

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Acknowledgements

We thank all study participants and staff of the Worker’s Hospital of the Jinchuan Nonferrous Metals Corporation (JNMC) for their generous work and the interviewers from the Institute of Epidemiology and Health Statistics, School of Public Health, Lanzhou University.

Funding

The study was supported by the National Natural Science Foundation of China (Grant Number: 41705122) and the research on the monitoring of ecological environment and health literacy of residents in Gansu, China (Grant Number: R20210005).

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Authors

Contributions

WZ: Formal analysis, Investigation, Methodology, Software, Writing. SZ: Conceptualization, Validation, Writing-Review and Editing, Supervision. YL: Investigation, Methodology, Manuscript revised. LZ: Investigation, Methodology. GS: Investigation, Software. XZ: Investigation. MW: Investigation, Data Curation. YN: Resources. Desheng Zhang: Resources. CY: Resources. YB: Project administration, Supervision.

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Correspondence to Shan Zheng.

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This study was approved by the medical ethics committee of school of public health of Lanzhou University (No. 2015-01).

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Zhu, W., Liu, Y., Zhang, L. et al. Ambient temperature variability and blood pressure in a prospective cohort of 50,000 Chinese adults. J Hum Hypertens (2022). https://doi.org/10.1038/s41371-022-00768-9

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