Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Can low-grade renal artery stenosis be considered as cause for renovascular hypertension?

This is a preview of subscription content

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Fig. 1

References

  1. Ritchie J, Alderson HV, Kalra PA. Where now in the management of renal artery stenosis? Implications of the ASTRAL and CORAL trials. Curr Opin Nephrol Hypertens. 2014;23:525–32.

    Article  PubMed  Google Scholar 

  2. Kwon SH, Lerman LO. Atherosclerotic renal artery stenosis: current status. Adv Chronic Kidney Dis. 2015;22:224–31.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Herrmann SM, Saad A, Textor SC. Management of atherosclerotic renovascular disease after Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL). Nephrol Dial Transplant. 2015;30:366–75.

    CAS  Article  PubMed  Google Scholar 

  4. Mousa AY, AbuRahma AF, Bozzay J, Broce M, Bates M. Update on intervention versus medical therapy for atherosclerotic renal artery stenosis. J Vasc Surg. 2015;61:1613–23.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Textor SC, McKusick MM. Renal artery stenosis: if and when to intervene. Curr Opin Nephrol Hypertens. 2016;25:144–51.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  6. Noory E, Sritharan K, Zeller T. To stent or not to stent? update on revascularization for atherosclerotic renovascular disease. Curr Hypertens Rep. 2016;18:45.

    Article  PubMed  Google Scholar 

  7. Fava C, Minuz P, Patrignani P, Morganti A. Renal artery stenosis and accelerated atherosclerosis: which comes first? J Hypertens. 2006;24:1687–96.

    CAS  Article  PubMed  Google Scholar 

  8. Urbieta-Caceres VH, Lavi R, Zhu XY, Crane JA, Textor SC, Lerman A, et al. Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney. Am J Physiol Ren Physiol. 2010;299:F135–40.

    CAS  Article  Google Scholar 

  9. Lerman LO, Taler SJ, Textor SC, Sheedy PF 2nd, Stanson AW, Romero JC. Computed tomography-derived intrarenal blood flow in renovascular and essential hypertension. Kidney Int. 1996;49:846–54.

    CAS  Article  PubMed  Google Scholar 

  10. Suresh M, Laboi P, Mamtora H, Kalra PA. Relationship of renal dysfunction to proximal arterial disease severity in atherosclerotic renovascular disease. Nephrol Dial Transplant. 2000;15:631–6.

    CAS  Article  PubMed  Google Scholar 

  11. Chade AR, Rodriguez-Porcel M, Grande JP, Krier JD, Lerman A, Romero JC, et al. Distinct renal injury in early atherosclerosis and renovascular disease. Circulation. 2002;106:1165–71.

    Article  PubMed  Google Scholar 

  12. Bartlett ES, Walters TD, Symons SP, Fox AJ. Quantification of carotid stenosis on CT angiography. Am J Neuroradiol. 2006;27:13–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Safak E, Wilke C, Derer W, Busjahn A, Gross M, Moeckel M, et al. Long-term follow-up of patients with atherosclerotic renal artery disease. J Am Soc Hypertens. 2013;7:24–31.

    Article  PubMed  Google Scholar 

  14. Dechering DG, Kruis HM, Adiyaman A, Thien T, Postma CT. Clinical significance of low-grade renal artery stenosis. J Intern Med. 2010;267:305–15.

    CAS  Article  PubMed  Google Scholar 

  15. Tollefson DF, Ernst CB. Natural history of atherosclerotic renal artery stenosis associated with aortic disease. J Vasc Surg. 1991;14:327–31.

    CAS  Article  PubMed  Google Scholar 

  16. Caps MT, Perissinotto C, Zierler RE, Polissar NL, Bergelin RO, Tullis MJ, et al. Prospective study of atherosclerotic disease progression in the renal artery. Circulation. 1998;25:2866–72.

    Article  Google Scholar 

  17. Schreij G, Ritsema GH, Vreugdenhil G, de Leeuw PW. Stenosis and renographic characteristics in renovascular disease. J Nucl Med. 1996;37:594–7.

    CAS  PubMed  Google Scholar 

  18. Gross CM, Kramer J, Weingartner O, Uhlich F, Luft FC, Waigand J, Dietz R. Determination of renal arterial stenosis severity: comparison of pressure gradient and vessel diameter. Radiology. 2001;220:751–6.

    CAS  Article  PubMed  Google Scholar 

  19. Bax L, Woittiez AJ, Kouwenberg HJ, Mali WP, Buskens E, Beek FJ, et al. Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial. Ann Intern Med. 2009;150:840–8.

    Article  PubMed  Google Scholar 

  20. Webster J, Marshall F, Abdalla M, Dominiczak A, Edwards R, Isles CG, et al. Randomised comparison of percutaneous angioplasty vs continued medical therapy for hypertensive patients with atheromatous renal artery stenosis. Scottish and Newcastle Renal Artery Stenosis Collaborative Group. J Hum Hypertens. 1998;12:329–35.

    CAS  Article  PubMed  Google Scholar 

  21. Van Jaarsveld BC, Krijnen P, Pieterman H, Derkx FH, Deinum J, Postma CT, et al. The effect of balloon angioplasty on hypertension in atherosclerotic renal-artery stenosis. Dutch Renal Artery Stenosis Intervention Cooperative Study Group. N Engl J Med. 2000;342:1007–14.

    Article  PubMed  Google Scholar 

  22. Murphy TP, Cooper CJ, Matsumoto AH, Cutlip DE, Pencina KM, Jamerson K, et al. Renal artery stent outcomes: effect of baseline blood pressure, stenosis severity, and translesion pressure gradient. J Am Coll Cardiol. 2015;66:2487–94.

    Article  PubMed  PubMed Central  Google Scholar 

  23. de Leeuw PW, Postma CT, Kroon AA. Treatment of atherosclerotic renal artery stenosis: time for a new approach. JAMA. 2013;309:663–4.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

AJJW was responsible for setup of the studies, for writing the paper, for the statistical analysis, for editing the paper as corresponding author. McdV did the data-collection and analysis, was co-writer of the paper, and draw the figure. PWdL was also responsible for the setup and structure of the paper. He assisted with statistical analysis, writing the paper, and editing the writing process.

Corresponding author

Correspondence to Arend J. J. Woittiez.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Woittiez, A.J.J., de Vogel, M.C. & de Leeuw, P.W. Can low-grade renal artery stenosis be considered as cause for renovascular hypertension?. J Hum Hypertens 36, 420–422 (2022). https://doi.org/10.1038/s41371-021-00628-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41371-021-00628-y

Search

Quick links