Fig. 1 | International Journal of Oral Science

Fig. 1

From: Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration

Fig. 1

Promoting endogenous bone regeneration and MSC recruitment with IMC in vivo. a SEM and EDS mapping of IMC and EMC. Arrows: apatite clusters. b Schematic diagram of a mandible defect and scaffold implantation. c Representative micro-CT and H&E staining images of the engineered bone with EMC and IMC at 2 weeks post implantation. NB new bone, IB immature bone, S scaffold. d Semiquantification of the neobone area. e Flow cytometry analysis of cell counts with EMC and IMC at 1 week post implantation. f Flow cytometry analysis of CD90+ cell numbers in the EMC and IMC groups

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