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Epidemiology and Population Health Production note

Lifestyle interventions along with vitamin D supplements on reducing leptinemia in obese man

International Journal of Obesity volume 44, pages 1626–1627 (2020)Cite this article

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We enthusiastically read “Relationships between circulating 25 (OH) vitamin D, leptin levels and visceral adipose tissue volume: results from a 1-year lifestyle intervention program in men with visceral obesity” by Gangloff et al. [1]. Although the findings support the inverse association between leptin and vitamin D and highlight the desirable effects of lifestyle interventions on reducing leptinemia, the methodology and study design are in need of further clarifications.

First, using a self-report 3-day dietary record to determine energy and nutrient intakes among various age groups from 30 to 65 years lacks validation because this record is more suitable for young participants [2]. Further, a sex-difference effect of energy intakes assessment was known for this dietary record because the males have a tendency to report less energy intakes compared with the females [2]. Given that participants were counseled by dieticians and kinesiologists during the interventions and the dietary questionnaire was given to those participants after the interventions at the 1-year follow-up visit, this practice may introduce a differential bias [3]. Specifically, those participants receiving from their dieticians the instructions about how to eat more healthy foods are more likely to self-report eating more of that food no matter their compliance. This type of bias may be attributed to the social desirability bias [4]. Therefore, the authors should discuss with the readers this potential for biased results.

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References

  1. Gangloff A, Bergeron J, Lemieux I, Tremblay A, Poirier P, Alméras N, et al. Relationships between circulating 25 (OH) vitamin D, leptin levels and visceral adipose tissue volume: results from a 1-year lifestyle intervention program in men with visceral obesity. Int J Obes. 2020;44:280–8.

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Authors and Affiliations

  1. Department of Health and Exercise Science, College of Health and Human Sciences, Colorado State University, Fort Collins, CO, 80523-1582, USA

    Xiang Gao

  2. Department of Epidemiology and Biostatistics, School of Public Health - Bloomington, Indiana University, Bloomington, IN, 47405, USA

    Haiping Wang & Aurelian Bidulescu

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  1. Xiang Gao
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  2. Haiping Wang
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  3. Aurelian Bidulescu
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XG is the primary and corresponding author of this letter. HW and AB reviewed, edited, and revised this letter. All authors contributed equally to this letter.

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Correspondence to Xiang Gao.

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Gao, X., Wang, H. & Bidulescu, A. Lifestyle interventions along with vitamin D supplements on reducing leptinemia in obese man. Int J Obes 44, 1626–1627 (2020). https://doi.org/10.1038/s41366-020-0599-2

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