Table 4 Changes in glucose and lipids in individuals who completed the study

From: Correction: Effect of intermittent compared to continuous energy restriction on weight loss and weight maintenance after 12 months in healthy overweight or obese adults

Parameter Baseline Following intensive period 12 months P value (time) P value (diet × time)
Glucose (mmol l−1)
CER 5.5 ± 0.4 5.4 ± 0.5 5.5 ± 0.6 0.25 0.77
WOWO 5.7 ± 0.5 5.5 ± 0.5 5.5 ± 0.5   
5:2 5.6 ± 0.6 5.5 ± 0.6 5.4 ± 0.6   
Cholesterol (mmol l−1)
CER 5.7 ± 1.1 5.7 ± 1.0 6.1 ± 1.2 <0.001 0.33
WOWO 5.7 ± 1.2 5.4 ± 1.2 5.7 ± 1.3   
5:2 5.8 ± 1.0 5.6 ± 1.0 5.9 ± 1.1   
Triglycerides (mmol l−1)
CER 1.2 ± 0.5 1.0 ± 0.5 1.0 ± 0.4 <0.001 0.50
WOWO 1.3 ± 0.7 1.0 ± 0.5 1.2 ± 0.8   
5:2 1.2 ± 0.5 0.9 ± 0.3 1.1 ± 0.5   
HDL (mmol l−1)
CER 1.5 ± 0.4 1.4 ± 0.4 1.6 ± 0.4 <0.001 0.11
WOWO 1.4 ± 0.4 1.4 ± 0.4 1.5 ± 0.4   
5:2 1.5 ± 0.5   1.6 ± 0.4   
LDL (mmol l−1)
CER 4.0 ± 1.0 4.1 ± 1.0 4.3 ± 1.1 0.004 0.16
WOWO 4.1 ± 1.0 3.8 ± 1.0 4.1 ± 1.2   
5:2 4.0 ± 0.9 4.0 ± 0.9 4.1 ± 1.0   
  1. Data presented as mean (SD). Available blood samples n = 138 (CER: n = 50, WOWO: n = 43, 5:2: n = 45)
  2. CER continuous energy restriction, HDL high-density lipoprotein cholesterol, LDL low-density lipoprotein cholesterol, WOWO week-on, week-off. Data analyzed by repeated measures ANOVA