Table 1 Comparison of cell cycle features (Refs. 8,14,24,42).

From: Maintenance of genome integrity and active homologous recombination in embryonic stem cells

  mESCs hESCs MEFs
Cell division time 12 h 16 h 24 h
S-phase length 7.5 h 8 h 4.8 h
CDK1 & CDK2 activity Very high Very high and periodical Periodical
RB phosphorylation status Hyperphosphorylation Hypo- and hyperphosphorylation Hypo- and hyperphosphorylation
HR protein expression +++ ++ +
  1. mESCs mouse embryonic stem cells, hESCs human embryonic stem cells, MEFs mouse embryonic fibroblasts