Fig. 1: A strategy for developing immunocompatible stem cells using the CRISPR/Cas9 system. | Experimental & Molecular Medicine

Fig. 1: A strategy for developing immunocompatible stem cells using the CRISPR/Cas9 system.

From: Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering

Fig. 1

a HLA allelic type of iPSCs used for immunocompatible cell development. b gRNA-targeted gene locus and sequence for HLA-B engineering. HLA-B.g2 (gRNA) was designed to target an exon of the HLA-B gene. c The vector map of the HLA-B.g2 plasmid. d Predicted region of the HLA-B protein deleted by the CRISPR/Cas9 system

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