Correction to: Journal of Human Genetics, published online 13 October 2022

Since the publication of this article, it has been brought to our attention, that the notation of methylated and unmethylated alleles was reversed. In the 15q11-q13 region, unmethylated alleles represent paternal alleles and methylated alleles represent maternal alleles. The correct text, figure and figure legend are shown below. The authors apologize for any inconvenience cause.

Agarose gel electrophoresis of PCR products showed both an obvious 100-bp band derived from the unmethylation allele and a faint 174-bp band derived from the methylation allele in the patient’s lane (Fig. 1B). This result suggested a mosaic status of methylated and unmethylated allele.

Fig. 1
figure 1

Methylation-specific PCR and microsatellite polymorphisms analysis. A Schematic drawing of methylation-specific PCR. Methylated fragment of 174 bp (primer sequences forward 5'-TAAATAAGTACGTTTGCGCGGTC-3' and reverse 5'-AACCTTACCCGCTCCATCGCG-3'), unmethylated fragment of 100 bp (primer sequences forward 5'-GTAGGTTGGTGTGTATGTTTAGGT-3' and reverse 5'-ACATCAAACATCTCCAACAACCA-3'). B 100-bp unmethylated allele indicates paternal allele.174-bp methylated allele indicates maternal allele. The lane of “AS” denotes DNA derived from the AS patient with demonstrated 15q11-q13 deletion for methylated allele-deficient control. C Genetic map of chromosome 15 and microsatellite markers. D Microsatellite polymorphisms analysis at ACTC locus. Blue and purple highlights indicate the same fragment length, respectively. Left: 26-cycle PCR fragments of patient, father and mother. Right: 35-cycle PCR fragments for magnification of maternally derived allele