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“Distribution of paternal lineages in Mestizo populations throughout Mexico: an in silico study based on Y-STR haplotypes”

Journal of Human Genetics volume 66, pages 327–332 (2021)Cite this article

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Abstract

The Mexican-Mestizo population arose following European contact with the Americas due to the admixture of principally Spaniards, Native Americans, and Africans around 500 years ago. Because the paternal lineage distribution of the Mexican population has been poorly investigated, this study inferred the haplogroups of ten populations based on 1859 haplotypes (Y-STR data) using two haplogroup predictor programs. In the Mexican population sample, we found predominantly European ancestry (50.1%), followed by Native American (32.5%), Eurasian (13.4%), African (2.1%), East African-South Eurasian (1.3%), and Asian (0.6%) ancestries. In general, our results support a contrary north-to-south gradient throughout the Mexican territory of European and Native-American ancestries, respectively. Moreover, the presence of West-European R1b and Sub-Saharan African E1b1a haplogroups agrees with historical and genetic data of gene flow during the European conquest. This study represents the effort to analyze these paternal lineages on a large scale by taking advantage of Y-STR haplotype data to determine the distribution and ancestry proportions in this country.

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Acknowledgements

We thank to CONACyT for the doctoral fellowship to JAA-V.

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  1. Instituto de Investigación en Genética Molecular, Universidad de Guadalajara (CUCiénega-UdeG), Ocotlán, Jalisco, México

    J. A. Aguilar-Velázquez & H. Rangel-Villalobos

  2. Doctorado en Genética Humana, Centro Universitario de Ciencias de la Salud (CUCS-UdeG), Guadalajara, Jalisco, México

    J. A. Aguilar-Velázquez

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  1. J. A. Aguilar-Velázquez
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Correspondence to H. Rangel-Villalobos.

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Aguilar-Velázquez, J.A., Rangel-Villalobos, H. “Distribution of paternal lineages in Mestizo populations throughout Mexico: an in silico study based on Y-STR haplotypes”. J Hum Genet 66, 327–332 (2021). https://doi.org/10.1038/s10038-020-00824-7

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