The Mongol Empire had a significant role in shaping the landscape of modern populations. Many populations living in Eurasia may have been the product of population mixture between ancient Mongolians and natives following the expansion of Mongol Empire. Geneticists have found that most of these populations carried the Y-haplogroup C3* (C-M217). To trace the history of haplogroup (Hg) C3* and to further understand the origin and development of Mongolians, ancient human remains from the Jinggouzi, Chenwugou and Gangga archaeological sites, which belonged to the Donghu, Xianbei and Shiwei, respectively, were analysed. Our results show that nine of the eleven males of the Gangga site, two of the eight males of Chengwugou site and all of the twelve males of Jinggouzi site were found to have mutations at M130 (Hg C), M217 (Hg C3), L1373 (C2b, ISOGG2015), with the absence of mutations at M93 (Hg C3a), P39 (Hg C3b), M48 (Hg C3c), M407 (Hg C3d) and P62 (Hg C3f). These samples were attributed to the Y-chromosome Hg C3* (Hg C2b, ISOGG2015), and most of them were further typed as Hg C2b1a based on the mutation at F3918. Finally, we inferred that the Y-chromosome Hg C3*-F3918 can trace its origins to the Donghu ancient nomadic group.
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Morgan D. The Mongols. New Jersey: Wiley-Blackwell; 2007.
Bentley JH. Old world encounters: cross-cultural contacts and exchange in pre-modern times. New York, NY: Oxford University; 1993.
Balaresque P, Poulet N, Cussat-Blanc S, Gerard P, Quintana-Murci L, Heyer E, et al. Y-chromosome descent clusters and male differential reproductive success: young lineage expansions dominate Asian pastoral nomadic populations. Eur J Hum Genet. 2015;23:1413–22.
Bai H, Guo X, Zhang D, Narisu N, Bu J, Jirimutu J, et al. The genome of a Mongolian individual reveals the genetic imprints of Mongolians on modern human populations. Genome Biol Evol. 2014;6:3122–36.
Zhong H, Shi H, Qi XB, Xiao CJ, Jin L, Ma RZ, et al. Global distribution of Y-chromosome haplogroup C reveals the prehistoric migration routes of African exodus and early settlement in East Asia. J Hum Genet. 2010;55:428–35.
Derenko MV, Maliarchuk BA, Wozniak M, Denisova GA, Dambueva IK, Dorzhu CM, et al. Distribution of the male lineages of Genghis Khan’s descendants in northern Eurasian populations. Genetika. 2007;43:422–6.
Zerjal T, Xue Y, Bertorelle G, Wells RS, Bao W, Zhu S, et al. The genetic legacy of the Mongols. Am J Hum Genet. 2003;72:717–21.
Abilev S, Malyarchuk B, Derenko M, Wozniak M, Grzybowski T, Zakharov I. The Y-chromosome C3* star-cluster attributed to Genghis Khan’s descendants is present at high frequency in the Kerey clan from Kazakhstan. Hum Biol. 2012;84:79–89.
Du R, Yip VF. Ethnic groups in China. Beijing: Science Press; 1993.
Lin G. A History of Donghu. Hohhot, Inner Mongolia: Inner Mongolia People’s Publishing House; 1989.
Sun J. The origin of Shiwei. Seeking Truth. 1985;1:88–94.
http://my.raex.com/~obsidian/earthrul.html. Accessed 20 June 2017.
Xin Wl, la T, Gang ZY. Lin Xi Jinggouzi: archaeological report and comprehensive research on the late bronze age cemetery. Beijing: Science Press; 2010.
Institute of Cultural Relics and Archaeology of Inner Mongolia Ulanqab Museum. Administration of Cultural Relics of Huade County. The excavation of Xianbei cemeteries of Chengwugou site in Huade county, Inner Mongolian. Cao Yuan Wen Wu. 2014;1:45–48.
Liu G, Bai J, Chen Y, Li C, Shen R. The excavation of Gangga site in Chen Barag Banner, Inner Mongolian. Archaeology. 2015;7:75–86.
Kayser M, Brauer S, Cordaux R, Casto A, Lao O, Zhivotovsky LA, et al. Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. Mol Biol Evol. 2006;23:2234–44.
Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF. New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. Genome Res. 2008;18:830–8.
Cui YQ, Li H, Ning C, Zhang Y, Chen L, Zhao X, et al. Y chromosome analysis of prehistoric human populations in the West Liao River Valley, Northeast China. BMC Evol Biol. 2013;13:216.
Wei LH, Huang YZ, Yan S, Wen SQ, Wang LX, Du PX, et al. Phylogeny of Y-chromosome haplogroup C3b-F1756, an important paternal lineage in Altaic-speaking populations. J Hum Genet. 2017;62:915–8.
Lkhagvasuren G, Shin H, Lee SE, Tumen D, Kim JH, Kim KY, et al. Molecular genealogy of a Mongol queen’s family and her possible kinship with Genghis Khan. PLoS ONE. 2016;11:e0161622. doi:10.1371/journal.pone.0161622
This work was supported by grants from the National Natural Science Foundation of China (Grant No. 31371266). We are grateful to Dr. Guoxiang Liu of the Institute of Archaeology, Chinese Academy of Social Sciences, and the Institute of Cultural and Historical Relics and Archaeology in the Inner Mongolia Nationality Autonomous Region in China for providing the samples.
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Y-chromosomal analysis of clan structure of Kalmyks, the only European Mongol people, and their relationship to Oirat-Mongols of Inner Asia
European Journal of Human Genetics (2019)