Table 2 Characteristics of Japanese registrees

From: Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan

   Male Female Average age at BRCA1/2 genetic test (youngest–oldest)
Pedigree 830    
Registreesa 3867 1176 2691  
 Subjectsb 944 22 922 46.9 (20–85)
 Othersc 2923 1154 1769  
Clients who received BRCA1/2 genetic testing 963 23 940 47.0 (20–85)
BRCA1 mutation positive 127 5 122 45.0 (23–79)
BRCA2 mutation positive 115 4 111 45.4 (23–74)
  1. aRegistrees consisted of subjects and the others
  2. bClients who provided informed consent at the time of registration in any of the four participating medical institutes
  3. cRegistrees within the second relatives of the subjects or uncles, who suffered from any cancers and registered by interview-based information