Table 3: Medical history of presenting complaints of subjects in the randomized arms at study baseline

From: A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants

Medical history of presenting complaints as examined by clinician, N (%)Test (N=35)Control (N=36)Total (N=71)
Overall symptoms   
 A change in behavior such as irritability or crying12 (34.3%)19 (52.8%)31 (43.7%)
    
Gastrointestinal symptoms   
 Frequent regurgitation or vomiting related to cow’s milk protein23 (65.7%)29 (80.6%)52 (72.3%)
 Persistent distress or colic (>3 h/day ≥3 days/week over a 3-week period)24 (68.6%)25 (69.4%)49 (69.0%)
 Soft stool constipation (with/without perianal rash due to infection)12 (34.3%)17 (47.2%)29 (40.8%)
 Faltering growth after the dietary inclusion of cow’s milk protein13 (37.1%)11 (30.6%)24 (33.8%)
 Extended periods of diarrhea with a negative stool examination8 (22.9%)9 (25.0%)17 (23.9%)
 Blood in stool10 (28.6%)5 (13.9%)15 (21.1%)
 Endoscopically confirmed eosinophilic enteropathy000
    
Skin symptoms   
 Eczema16 (45.7%)21 (58.3%)37 (52.1%)
 Urticaria3 (8.6%)4 (11.1%)7 (9.9%)
    
Respiratory symptoms   
 Sneezing/nasal congestion9 (25.7%)12 (33.3%)21 (29.6%)
 Wheezing5 (14.3%)5 (13.9%)10 (14.1%)
 Conjunctivitis1 (2.9%)3 (8.3%)4 (5.6%)
 Dyspnea1 (2.9%)1 (2.8%)2 (2.8%)
 Stridor1 (2.9%)1 (2.8%)2 (2.8%)
 Dysphonia000
 Aphonia000
    
Other symptoms   
Hypotension for age000
    
Predominant complaint/stratification factor   
 Skin symptoms4 (11.4%)3 (8.3%)7 (9.9%)
 Gastrointestinal symptoms31 (88.6%)33 (91.7%)64 (90.1%)