Figure 3

From: A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants

Figure 3

Parent-reported, clinician-evaluated symptoms at weeks 0, 1, 4, and 8 assessed on a 4-point rating scale specific for each symptom. Skin symptoms (redness, oozing, crusting, itchiness, dryness, and nappy rash) were rated as 1: none, 2: slight, 3: some, and 4: a lot. Respiratory symptoms blocked nose and wheezing rated as 1: none, 2: mild, 3: moderate, and 4: severe, and coughing was rated as 1: none, 2: one to two times/day, 3: three to five times/day, and 4: more than five times/day. General and gastrointestinal symptoms: vomiting was rated as 1: none, 2: one to two times/day, 3: three to four days/day, and 4: more than four times/day; spitting-up as 1: none, 2: after some feeds, 3: after all feeds, and 4: between and after feeds; gas/wind as 1: none; 2: slight; 3: some; and 4: a lot; sleep pattern last night as 1: normal, 2: awake once, 3: awake two to three times, and 4: awake more than three times; ease of settling or burping after feeds as 1: no problem at all, 2: slight difficulty, 3: some difficulty, and 4: very difficult; visual signs of discomfort (e.g., back arching) as 1: none, 2: slight, 3: some, and 4: a lot; and crying (because of irritability) as 1: none, 2: up to 1 h, 3: 1–3 h, and 4: more than 3 h. Data are shown as mean values±95% confidence interval limits.