Abstract
Purpose: Operations of children with intellectual disabilities have been questioned by some because of suspicion of a poor outcome.
Methods/material: Retrospective study of all Danish children (n=65) operated between 1996 and 2007. 25 children had an IQ/DQ above 70 (group A) and 40 had IQ/DQ of 70 or below (group B). Mean age at operation in group A were 13 years and in group B 9 years and 1 month. In group A the majority (17) were operated in Denmark, and in group B the majority (16) were operated abroad mainly Cleveland Clinic, USA. In group A 4 had hemispherectomy or multiple lobe resection whereas in group B 19 children had this kind of operation.
Results: Seizure free outcome (Engel 1 A or B) were found in 68,0% (group A) and 67,5% (group B) at one year follow op. In group A 27,3% had an increase and 18,2% a decrease of 10 IQ/DQ or more compared to 10,0% and 14,0% in group B one year after the operation.
Behavioural changes (mood, agression) were registered by the parents at a visit 6-8 weeks after the operation. In group A 45% of the parents reported an improved situation, compared to 34% in group B. Only 10% of the parents in group A reported an improved “attention and energy” compared to 47% in group B.
Conclusion: Seizures and developmental outcome after epilepsy surgery did not differ in a Danish cohorte comparing children with intellectual disabilities with normal children.
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Uldall, P. 245 Influence of Iq/Dq on Outcome in Childhood Epilepsy Surgery. Pediatr Res 68 (Suppl 1), 127 (2010). https://doi.org/10.1203/00006450-201011001-00245
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DOI: https://doi.org/10.1203/00006450-201011001-00245