Abstract
Introduction and objectives: infection by Enterobacteriaceae which are resistant to carbapenems is challenging problem in health care centers. The correct monitoring of patients for treatment by carbapenems was one of the most significant considering in this study.
Methods: the urine samples of patients were gathered during six months. E.coli and Klebsiellae strains were detected. Susceptibility testings such determining of MIC and agar diffusion agar were performed for meropenem and imipenem for these strains and then carbapenemase coding gene detected by PCR method.
Results: 197 strains isolated fro urine samples in which 138 E.coli and 58 Klebsiella pneumoniae were detected. 5 strains of E.coli (3.6 %) and 3 strains of Klebsiella (5.1%) were resistant to Imipenem and Meropenem and then kpc2 and kpc3 genes of their resistance were detected by PCR.
Conclusion: there is no any comprehensive program for screening of resistant strains of bacteria to carbapenems in our country and worldwide but epidemiologic increasing of these strains should be considered.
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Sanaei, A., Karimi, A., Malekan, M. et al. 1397 Detection of Resistance to Carbapenems in E.Coli and Klebsiella Pneumonia From Urine of Children with Uti in Mofeed Children Hospital. Pediatr Res 68 (Suppl 1), 691 (2010). https://doi.org/10.1203/00006450-201011001-01397
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DOI: https://doi.org/10.1203/00006450-201011001-01397