Abstract
Aim: Infants with Hypoplastic Left Heart Syndrome(HLHS) may suffer inhibited growth. Some papershave shown it in congenital heart disease. Aim:to check if that is true in HLHS. We will also studyother perinatal parameters that can be influencedby this pathology.
Methods: We have studied a total number of 173HLHS of which 75 (43,45 %) died in our neonatalunit. We have compared data of maternal, pregnancy and delivery risks, weight, height andcephalic perimeter with normal babies born in thesame period in our hospital,. We also compared theevolution between babies born at our hospital andthose who were referred to us.
Results: No difference was obtained betweennormal and HLHS groups on: maternal age, number of previous gestations, abortion and livebabies. There was significant difference in maternalpathology especially due to endocrine alterations(thyroid and diabetic). Also epilepsy was present. Both weight (3216,05 v 2990,39 p< 0,001) andcephalic perimeter (34,26 v 33,41 p< 0,001) wassignificantly different. Height had a p< 0,1. At birthpH, Apgar 1 minute were significantly diminished inthe HLSH group.
HLSH born at our hospital had less morbidity andmortality.
Conclusions: We think it is important to diagnosepregnancy growth retardation and try to control it. Asother authors have shown aortic arch morphometryduring pregnancy should be controlled. Endocrinepathology or epilepsy in the mother may be a riskfor HLSH. It is advisable that these babies shouldbe born in reference hospitals.
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Sheriff, V., Luna, M., Bravo, D. et al. 1302 Epidemiology of the Hypoplastic Left Heart Syndrome: Importance of An Accurate Diagnosis During Pregnancy. Pediatr Res 68 (Suppl 1), 644 (2010). https://doi.org/10.1203/00006450-201011001-01302
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DOI: https://doi.org/10.1203/00006450-201011001-01302