Acquisition curves in the water maze task in rats. Each block: swimming time (A), swimming length (C), swimming speed (E). Average of the all blocks: swimming time (B), swimming length (D), swimming speed (F). The task was started after 16 wk of recovery from HI treatment, and three trials were performed per day for 5 d. The no training HI group (□; n = 16) had significantly greater swimming lengths compared with the pretraining HI group (▪; n = 15), whereas the no-training control group (○; n = 16) showed the equivalent time and length to the pretraining control group (•; n = 15). Repeated-measures two-way ANOVA was also used to evaluate the results of water maze, followed by Tukey's test for post hoc analysis.*p < 0.05 and **p < 0.01 comparing the no training HI and pretraining HI groups in A and C. Tukey's test after one-way ANOVA was used in comparison of all blocks averages between four groups.