Previous studies calculated and validated a predictive model (PM) which selects infants who suffer up to 5 times more acute infectious illnesses and deteriorate their anthropometric parameters in comparison with unselected peers. Objective: to follow up morbidity and anthropometric parameters in children defined at risk by the model during their first year of life, now aged 5 to 6y. 215/315 families with PM (+) studied between 1989-1993 were reevaluated (G2) and contrasted with 215 whose PM was (-)(G1), paired by sex and age of index child. Results: some characteristics which were formerly associated with the risk persisted in G2: they consulted less frequently at primary health care services and emergency rooms (p<0.001), had incomplete immunizations more frequently (p<0.08), attended less nurseries and presschool centers (p<0.03), number of children per family was less (p<0.03), absent father in the family was more frequent (p< 0.04); lacked minimal housing facilities more frequently (p< 0.04). In G2 children presented higher incidence of lower respiratory diseases (p< 0.05) and skin infections (p< 0.09) but not diarrhea. Indicators of quality of life showed that mothers in G2 spent more time out of home (p< 0.000) and left the child with different persons more frequently (p< 0.000). Changes in Weight/Age was similar in both groups. Height/Age was significantly less in G2 at 2 years of age (p< 0.004) but the difference dissappeared at 6y. Conclusions: children who were at health risk during the first year of life continued suffering more respiratory and skin morbidity during the preschool age but not diarrhea. Some maternal respiratory ans skin morbidity during the preschool age but not diarrhea. Some maternal inadequate behaviors associated with the risk were still present. In G2, although at 2 years of age Height/Age was significantly less, at 6 years the difference disappeared. The meaning of poorer parameters of quality of life deserves further investigation. FONDECYT 195-0237.