To evaluate how the sex and bilitubin levels could induce abnormalities in latency wave I and V we studied the brainstem auditory evoked reponses in neonates with hyperbilirubinemia. We analysed 29 female neonates with total bilirubin levels of 17,88±4,29 mg/dl and 51 male neonates with total bilirubin levels of 18,87±4,62 mg/dl until 48 hours of life. Latence I-V were measured by BERA using monoaural 120 dB click stimuli in Amplied MK 15. Abnormal BERA was defined as latencies I-V > 5.5 ms. Statistical analysis was performed by Mann-Withney test:
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Male - p values: (BT) - 0.321 / (P I - V) - 0.5745
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Female - p values: (BT) - 0.321 / (P I - V) - 0.4668
We concluded that sex cannot be indicated as a risk factor of hyperbilirubinemia and prolongation of P I - V. Moreover, studies in males with neonatal hyperbilirubinemia accompanhied at 18 years of age should be observed minor handcap.
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Gallacci, C., Vaz, F., Berezin, A. et al. Influence of Sex in Neurotransmissor Evaluation by Brainstem Auditory Evoked Responses (BERA) in Healthy Term Infants with Hyperbilirubinemia 1010. Pediatr Res 43 (Suppl 4), 174 (1998). https://doi.org/10.1203/00006450-199804001-01031
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DOI: https://doi.org/10.1203/00006450-199804001-01031