Background: Following a paper by Mock et al (N Engl J Med 1983; 309: 764-71) reporting retarded growth in 2 patients with hereditary fructose intolerance (HFI), growth was studied in 47 patients with HFI.
Subjects: The charts of 47 patients (22 boys and 25 girls) with HFI were reviewed.
Interventions: The patients were divided into 4 groups according to age (0-6 years, 6-11 years, 11-17 years, and > 17 years). Heights and weights were compared to controls previously established. Fructose daily ingestion was clinically controled.
Results: Growth retardation was not found in either groups.
Conclusions: By contrast to the report by Mock et al, these results show that a clinically controled fructose-free diet is efficient to allow normal growth in HFI children.
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Chevalier, P., Trioche, P., Odièvre, M. et al. Patterns of Growth in Hereditary Fructose Intolerance 53. Pediatr Res 40, 524 (1996). https://doi.org/10.1203/00006450-199609000-00076