Abstract
We investigate if infantile obesity could associate to hyperinsulinism, insulin resistance, hyperandrogenism by ovarian hyperstimulation and decrease in the SHBG levels in serum, mediated by means of the IGF-I receptors. 29 obese and 9 normal girls underwent an oral glucose tolerance test with insulin dosage by RIA at 0-30-60 and 120 minutes, and:T3 and T4 by RIA, TSH, LH, FSH, PRL, IGF-I and SHBG by IRMA. a) Clinical characteristics of both groups (X±SD)
b) Oral glucose tolerance test (X±SD)
c) Other determinations
Infantil obesity associated with hiperinsulinism could lead to hyperandrogenism.
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Rubio, G., Bergoglio, L., Muñoz, L. et al. 23 METABOLIC-HORMONAL CHANGES IN INFANTIL OBESITY. Pediatr Res 36, 676 (1994). https://doi.org/10.1203/00006450-199411000-00047
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DOI: https://doi.org/10.1203/00006450-199411000-00047