Abstract
We investigated the relation between obesity and lipid and apoprotein levels in 286 children, 6-14 years aged, 133 males and 153 females (16.5% with obesity). Weight, height and skinfolds were calculated for each child. Serum samples were collected after 12 hours fast; total cholesterol (TC), triglycerides (TG) and HDL cholesterol (HDLC) were determined by an enzymatic, dry multilayer method (Kodak Ektachem DT60); LDL cholesterol (LDLC) was calculated by Friedewald's formula; apoprotein B (ApoB) and AI (ApoAI) were measured by a nephelometric method. We considered obese a child with an over-weight>20% ideal weight. Statistical analysis was performed by two way (sex and obesity) analysis of variance to test the differences of lipoproteins in male and female obese children. TC and TG were higher in obese children, both in males and females. HDLC was lower in female but not in male obese children; LDLC was higher in obese females. No difference was observed in ApoAI levels, ApoB was higher in female obese children, but not in male ones. In females, the stronger correlation was found between ApoB and % overweight (r=0.31, P=0.001).
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Bellù, R., Mt, O., Scaglioni, S. et al. 160 LIPID AND APOPROTEIN LEVELS IN OBESE SCHOOL CHILDREN. Pediatr Res 28, 303 (1990). https://doi.org/10.1203/00006450-199009000-00184
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DOI: https://doi.org/10.1203/00006450-199009000-00184