Abstract
In neonates antimicrobial treatment is an important factor to acquire Candida, with risk of subsequent systemic infection. We prospectively studied the acquisition of candida, in term vs. preterm infants, who were treated with ampicillin in combination with an aminoglycoside.
185 infants were studied; infants who acquired candida before antibiotic treatment, were excluded (n=13). The remaining infants were grouped according to their gestational age.
Of the 172 infants, 31 acquired candida (=18%) 3 of the latter developed systemic candidiasis.
Conclusion: There is no significant difference in incidence in Candida acquisition between the different gestational age groups. In particular infants with a gestational age of 32 weeks or less seem to be at risk for systemic candidiasis.
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Baarsma, R., Dankert, J. & Okken, A. IS CANDIDA ACQUISITION IN THE INTENSIVE CARE NEONATE DURING ANTIBIOTIC TREATMENT RELATED TO GESTATIONAL AGE? A PROSPECTIVE STUDY. Pediatr Res 26, 509 (1989). https://doi.org/10.1203/00006450-198911000-00062
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DOI: https://doi.org/10.1203/00006450-198911000-00062