Abstract
Real-time ultrasonography of the pelvic organs was performed on 40 girls with PT, 31 with PA, 23 with PP, 39 with EP, 18 with isolated vaginal heeding (VB), 20 with congenital adrenal hyperplasia (CAH), 20 with hirsutism (H), 18.with obesity (0) and 133 age-matched normal girls (C). Uterine and ovarian volumes (UV and OV) were calculated and ovarian morphology was classified as SO1= homogenous, SO2= less than 3 small cystic areas, SO3= microcystic, SO4= at least one cystic area >9 mm and C= large cystic area up 20 mm.
Examination revealed: pictures resembling aged-matched controls in PA and 0; higher SO2 frequency in PT and CAH under 8 years (with higher 17-OH-P values); higher SO3 frequency in H (with higher testosterone values); macrocysts (C) in V8, H and CAH over 10 years.
OV was higher than controls in PP and EP with SO3 and SO4, in II and 0 with SO3. UV was higher than control in PP and EP with SO3 and SO4; lower in CAH over 10 years.
Real-time ultrasonography of the pelvic organs can be very useful not only in diagnosing disorders in sexual development but also for greater understanding at the pathogenesis of these disorders.
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Salardi, S., Orsini, L., Reggiani, A. et al. PELVIC ULTRASONOGRAPHY IN PREMATURE THELARCHE (PT), PREMATURE ADRENARCHE (PA), PRECOCIOUS PUBERTY (PP), EARLY PUBERTY (EP) AND OTHER ENDOCRINE ABNORMALITIES. Pediatr Res 23, 128 (1988). https://doi.org/10.1203/00006450-198801000-00163
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DOI: https://doi.org/10.1203/00006450-198801000-00163