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RECURRENT OTITIS MEDIA AND CHRONIC SINUSITIS (OM/SIN) ARE COMMON PRESENTING FEATURES AND COMPLICATIONS IN PEDIATRIC HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION

Abstract

Although recurrent bacterial sepsis and pneumonia have been reported in pediatric HIV infection, OM/SIN generally are not considered paramount features of the disease. The present report indicated that OM/SIN are often the earliest signs of immunologic compromise. Since 1982, 26 non-hemophiliac children 18M, 8F with HIV infection have been seen. 15 patients (pts), were infected through blood transfusions (TX) and 11 through maternal passage. 13 pts, 12M, IF, presented with OM (11) or SIN (2) 1 month to 3 years before diagnosis of HIV infection. 9 of these pts had chronic oral candidiasis which had been attributed to use of antibiotics; 9 were failure to thrive attributed to recurrent upper respiratory infections. 11 of these 13 pts had signs and radiographic findings indicative of SIN. 5 pts had undergone otologic surgery prior to diagnosis of HIV. All 13 pts had elevated IgG levels and 12 had T-cell immunodeficiency. Of the 13 pts whose earliest signs were other than OM/SIN, 5 developed OM and 4 SIN since diagnosis of HIV infection. 5 of these pts had normal IgG levels, 1 had hypo-IgG and 12 had T-cell deficiency. 10 of 15 (67%) of pts infected with HIV through TX presented with OM/SIN in contrast to 3 of 11 (27%) of pts with maternally-transmitted HIV. The prevalence of OM (61%) and SIN (57%) in this patient population has not been reported previously, and may be related to the route of HIV infection in these children.

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Church, J. RECURRENT OTITIS MEDIA AND CHRONIC SINUSITIS (OM/SIN) ARE COMMON PRESENTING FEATURES AND COMPLICATIONS IN PEDIATRIC HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION. Pediatr Res 21, 309 (1987). https://doi.org/10.1203/00006450-198704010-00854

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  • DOI: https://doi.org/10.1203/00006450-198704010-00854

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