Abstract
We studied 200 11 year-old twin pairs and their parents and asked: 1) Is there a relationship of CF with systolic blood pressure (SBP)? 2) Are there sex differences and do they relate to sexual maturity? 3) Do measures of CF relate to SBP in adults? Significant relationships of SBP to anthropometric measures are tabulated (p< .05).
Girls were more sexually mature than boys (Tanner = 2.5 vs 2.0 p<.001). In mothers but not fathers SBP correlated both with weight (r=0.26) and SI (r=0.29) In a model using height, weight, and CF to explain the variance of SBP in girls, only CF was significant r2 =17%. We conclude: 1) CF explains a significant proportion of the variance of SBP in girls, 2) These effects appear to be influenced by sexual maturity 3) the relationship of CF to SBP is seen in mothers but not fathers which further suggests that female sexual hormones may mediate this process.
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Bodurtha, J., Schieken, R., Mosteller, M. et al. DOES CENTRAL FAT DEPOSITION (CF) DETERMINE SBP: MCV HEART STUDY. Pediatr Res 21 (Suppl 4), 187 (1987). https://doi.org/10.1203/00006450-198704010-00125
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DOI: https://doi.org/10.1203/00006450-198704010-00125