Abstract
A comparative study of plasma amino acids in the umbilical cord (aa)(totals and ratios: malnutrition indices) dnd clinical nutritive state by Rohrer's ratio(Rr) between well nourished premature (GI) and undernourished neonates born at term (GII). Patiens groups:GI(n:30), GA:33.9(.3) (+/-SEM)wk, Wt:2084(.06)g and Rr:25.1(3.6)p;GII(n:14), GA:38.2(.3) wk, Wt:2328(.05)g, Rr:8.14(4.2)p. Blood sampling: .5 ml UVB was mixed with EDDA and centrifuged immediately. Sulfosalisylic acid was then used to separated proteins from plasma. The supernatant was either used immediately or stored at -20°C. Technical analysis: HPIECH and fluorimetric assay (Chromaspeck J 180). Statistical study: Student's and Welch's tests, (aa) concentrations are expressed in micromol/dl. (versus:-;$:p .05).
RESULTS.- GII-GI: S:460(28)-436(21); E:136(7)-145(7); NE:323(24)-291(18); NE/E:2.4 (.1)-2.0(.1); BCA:37(1.9)-46(2.4)$; ALA/THR:1.9(.1)-1.3(.1)$; GLY/VAL:2.2(.4)-1.2(.1)$; ALA/LEU:5.0(.5)-2.9(.1)$; ALA/BCA:1.6 (.1)-0.9(.1)$; and, PHE/TYR:1.2(.1)-1.3(.1). There are a close correlation between ALA:LEU (r: .72, p<.01) in GII but not in GI. We conclude that undernourished neonates born at term has strongly activated the alanine-glucose cycle. The BCA catabolized in muscle provide a major nitrogen source for biosynthesis of alanine which play and important role in energy metabolism.
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Bayes, R., Maldonado, J., Vazquez, J. et al. BRANCHED CHAIN AMINO ACIDS AND PERINATAL NUTRITIVE STATE. Pediatr Res 22, 232 (1987). https://doi.org/10.1203/00006450-198708000-00113
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DOI: https://doi.org/10.1203/00006450-198708000-00113