Abstract
Chlamydia trachomatis (Ct) is believed to be a cause of LRIs mainly in young infants. Close surveillance for LRIs was maintained since birth on a group of 1182 children. Over a period of 17 months, we obtained nasopharyngeal and throat swabs for acute LRI from 340 children. All specimens were cultured for viruses, Ct and Mycoplasma pneumoniae. One or more of these agents were isolated from 67% of LRIs. Ct was isolated from 3/52 (5.8%) of infants ≤6 months of age, 0/61 (0%) infants 7-12 months and 9/227 (4.0%) children 1-3 years with LRI. Infection with Ct in these 9 older children (ages 17-34 mos, med=21 mos) occured from December to April and was associated with a variety of syndromes and with concurrent isolation of other pathogens.
Symptoms and signs included cough (9), rhinitis (8), fever (3), abnormal bronchial breath sounds (3), hoarseness (2), shortness of breath (2), stridor (2) and wheezing (1).
These results suggest that Ct is associated with a diversity of LRIs in children >1 year of age, and may often be present with other pathogens.
(Supported by NHLBI-SCOR Grant HL-14136)
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Shehab, Z., Ray, C., Minnich, L. et al. 1161 CHLAMYDIA-ASSOCIATED LOWER RESPIRATORY TRACT INFECTIONS (LRI) IN CHILDREN OVER 1 YEAR OF AGE. Pediatr Res 19, 304 (1985). https://doi.org/10.1203/00006450-198504000-01191
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DOI: https://doi.org/10.1203/00006450-198504000-01191
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