Abstract
Sixty-seven children, with a mean age of 30 months, attending a day care center had urine samples cultured for cytomegalovirus (CMV) 3 times over 6 months. Twenty-one children had CMV viruria. Viruria did not correlate with the length of day care center attendence nor age. The prevalence of CMV viruria among these children (32%) was significantly higher then among a group of 926 age-matched hospitalized children. Of this group, 64 (6.9%) had CMV viruria. (X2=49, 1df, p<0.0001, when compared to day care center children). Restriction endonuclease digestion using EcoRI, of the DNAs of 14 of the CMV isolates, revealed only 7 different patterns, two sets of 4 children and one set of 2 children had identical patterns. In contrast, EcoRI digestion of the DNAs of 13 randomly selected CMV isolates from the hospitalized children revealed 13 different patterns. These results prove that CMV was frequently transmitted among children attending the day care center.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Adler, S., Wilson, M. & Lawrence, L. 1047 CYTOMEGALOVIRUS TRANSMISSION AMONG CHILDREW ATTENDING A DAY CARE CENTER. Pediatr Res 19, 285 (1985). https://doi.org/10.1203/00006450-198504000-01077
Issue Date:
DOI: https://doi.org/10.1203/00006450-198504000-01077