Abstract
We studied BP patterns and the Renin-Angiotensin-Aldosterone axis (RAA) of 97 IDDM children (3-15 yrs old) in relation to the auxological data,the metabolic control and duration of diabetes (1-13 yrs).We analysed a total of 712 BP measurements. RESULTS. Mean systolic BP levels for age groups were at the 50th percentile of the general population,while the mean diastolic BP were at the 75th in both sexes.Systolic and diastolic BP levels were directly and significantly related to age, weight,height,Quetelet index,duration of disease and HbA1. Plasma Renin Activity (PRA) levels,all within normal limits, were related neither to age,Natruria and Kaliuria (contrary to normal children) nor to the parameters of metabolic control. CONCLUSIONS. BP levels were not grossly altered but were under the influence of metabolic control. The absence of a correlation between PRA and age or electrolytes excretion suggest an early disturbance of RAA, probably caused by concomitant metabolic alterations.
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Virdis, R., Terzi, C., Boselli, E. et al. Blood pressure (BP) and metabolic control in IDDM. Pediatr Res 18, 1221 (1984). https://doi.org/10.1203/00006450-198411000-00120
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DOI: https://doi.org/10.1203/00006450-198411000-00120