Abstract
A simple system for predicting fetal macrosomia has been developed, involving three risk factors: 1)Glucose intolerance, 2)History of macrosomia and 3)Maternal obesity. To date, 305 infants have been delivered from 302 prospectively screened mothers. The frequencies of risk factors were: 1)Obesity 25%, 2)Glucose intolerance 7.6% and 3)History of macrosomia 7.0%. Thirty one infants (10.1%) were macrosomic (>4000 g) and/or large-for-gestational age (LGA). Overall, the sensitivity of the screening method was 61%. Obesity was the predominant risk factor (48%) among mothers of macrosomic infants, while glucose intolerance was present in only 17%. The macrosomic infants from "at risk" mothers were characteristically LGA (90%) compared to those from normal mothers (50% LGA) (p<.02). The LGA-Macrosomic group of infants were younger (38.8 vs. 41.4 weeks) but heavier (4290 vs. 4062 g) than the AGA-Macrosomic group. They exhibited a significant increase in skinfold thickness, but no difference in length or head circumference compared with the AGA-Macrosomic Group. There appears to be two dinstinct groups of macrosomic infants: those who are asymmetrically large, and those who are symmetrically large, but post-term. If gestational age of 41 weeks or greater is included in the scoring system, 77% sensitivity is achieved in predicting these combined groups. (Supported in part by grants from the Bay Area March of Dimes and the Nestle Co.-USA)
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Green, J., Partridge, J., Perry, J. et al. PREDICTION OF FETAL MACROSOMIA. Pediatr Res 18 (Suppl 4), 330 (1984). https://doi.org/10.1203/00006450-198404001-01424
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DOI: https://doi.org/10.1203/00006450-198404001-01424