Abstract
Higher incidence of abnormal ventilatory response was found in two of three groups of infants tested with a computerized CO2 waveform analyzer that measures breath by breath responses. Forty nine infants (BW 1980±1010g, GA 33±5wks) with risk factors (prolonged apnea, BPD), 11 near miss (BW 3090±760g, GA 39±2wks), and 6 siblings of SIDS (BW 3310±1090g, GA 39±4wks) comprised the three groups. Age at evaluation was 44±10wks postconceptual age for risk infants, 54±14 wks for the near miss group, and 49±18 wks for siblings.
The risk group slope was significantly greated that the sibling group slope (P<0.05). The difference between risk and near miss slopes did not reach statistical significance. Nine risk infants (18%), 6 near miss (54%), and 3 siblings (50%) were identified to have abnormal slopes, below 20 mm/kg/min/mmHg BTPS (P<0.05). Near miss and sibling infants demonstrated more blunted responses to CO2 that a group identified to be at risk.
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Marotta, F., Fort, M., Mondestin, H. et al. THE RESPONSE TO CO2 IN INFANTS AT RISK FOR SIDS. Pediatr Res 18 (Suppl 4), 327 (1984). https://doi.org/10.1203/00006450-198404001-01406
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DOI: https://doi.org/10.1203/00006450-198404001-01406