Cavum vergae is a midline cavity of the brain, posterior to the septum pellucidum which often communicates with a cavum septum pellucidum. While the clinical significance of this anatomic finding is not clear, we have seen 6 pediatric patients with cavum vergae who had neurologic abnormalities. They ranged from 3 weeks to 4 years of age at the time of presentation. The reason for initial evaluation was large head size in 3 patients, dysmorphic facies in 2 patients, and seizure associated with fever in one patient. The diagnosis of cavum vergae was made by CT scan of the brain - 2 of the 6 had only a cavum vergae while 4 had a cavum vergae and cavum septum pellucidum. It is significant that 5 of the 6 patients had developmental delay, and 4 had head circumferences ≥97th percentile without radiographic evidence of gross hydrocephalus. Two of the patients with large head circumferences were thought to have cerebral gigantism. To determine the background frequency of cavum vergae in children without apparent neurologic abnormality, we reviewed 50 CT scans of the brain in children between 4 months and 5 years of age whose CT scans were done for head trauma and found no cases of cavum vergae. These observations suggest that cavum vergae can be associated with neurologic dysfunction and macrocephaly.
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Miller, M., Horner, F. & Kido, D. CAVUM VERGAE AND NEUROLOGIC ABNORMALITIES. Pediatr Res 18 (Suppl 4), 307 (1984). https://doi.org/10.1203/00006450-198404001-01282