Abstract
To study effect of hypermagnesemia on neurologic estimate of gestational age (EGA), 3 groups of neonates were identified: Group A - hypermagnesemic (HM) infants of magnesium sulfate (MS) treated pre-eclamptic mothers. Cord blood magnesium (CBM) was 4.2 ± 0.7 mg/dl. Group B - non HM infants (CBM 1.5 ± 0.2 mg/dl) of untreated pre-eclamptic mothers. Group C - control infants (CBM 1.6 ± 0.2 mg/dl) of normal, non-MS treated mothers. Serial EGAs were done by method of Dubowitz, et al. Scores from neurologic section of the exam are given as mean ± 1 S.D. EGA is given in weeks.
EGAs of B & C did not significantly vary over 48 hrs. EGAs of A varied as much as 5 weeks. EGA, therefore, is unreliable by this method in HM infants less than 48 hrs. of age.
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Rasch, D., Huber, P., Richardson, C. et al. 361 EFFECT OF HYPERMAGNESEMIA ON NEUROLOGIC SECTION OF DUBOWITZ EXAM. Pediatr Res 15 (Suppl 4), 500 (1981). https://doi.org/10.1203/00006450-198104001-00372
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DOI: https://doi.org/10.1203/00006450-198104001-00372